Semaglutide API Synthesis Peptide for Diabetics CAS NO.910463-68-2 CAS NO.910463-68-2

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Product name:Sermaglutide

CAS No.:910463-68-2

Molecular formula:C187H291N45O59

Molecular weight:4113.64

Purity:98%

Semeglutide is a long-acting glucagon-like peptide 1 (GLP-1) analog, a GLP-1 receptor agonist, and has potential therapeutic efficacy in type II diabetes mellitus (T2DM).

Compared with liraglutide, semaglutide has a longer aliphatic chain and increased hydrophobicity, but semaglutide is modified with a short chain of PEG, and its hydrophilicity is greatly enhanced. After PEG modification, it can not only bind closely to albumin, cover the enzymatic hydrolysis site of DPP-4, but also reduce renal excretion, prolong the biological half-life, and achieve the effect of long circulation.